The 2022 NFL season kicks off in a big way as the defending champion Rams host the Bills on Thursday Night Football. Albert Breer, Michael Fabiano and Jen Piancenti break down what could be a Super Bowl preview with everything you need to know about the matchup, fantasy and betting. #NFL #Bills #Rams ---------------------------------------------------------------------------------------------------------- Subscribe to SI on YouTube! https://www.youtube.com/channel/UCPAt6z5uX_c5Eo_cSNROzYw?sub_confirmation=1 Subscribe to SI today for access to the biggest teams, the boldest names, and the legendary stories that only we can deliver: https://trib.al/ERqIwSS Check out SI.com: https://trib.al/MQ4bEWM Follow SI on all social channels! Twitter: https://twitter.com/SInow Facebook: https://www.facebook.com/SportsIllustrated/ Instagram: https://www.instagram.com/sportsillustrated TikTok: https://www.tiktok.com/@sports.illustrated